7QPI

Structure of lamprey VDR in complex with 1,25D3

7QPI の概要

• エントリーDOI: 10.2210/pdb7qpi/pdb
• 分子名称: Vitamin D receptor, Nuclear receptor coactivator 1, 5-{2-[1-(5-HYDROXY-1,5-DIMETHYL-HEXYL)-7A-METHYL-OCTAHYDRO-INDEN-4-YLIDENE]-ETHYLIDENE}-4-METHYLENE-CYCLOHEXANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: vdr, complex, agonist, transcription
• 由来する生物種: Petromyzon marinus (sea lamprey); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 34463.16

構造登録者

Rochel, N. (登録日: 2022-01-04, 公開日: 2022-12-14, 最終更新日: 2024-01-31)

• 主引用文献: Sigueiro, R.,Bianchetti, L.,Peluso-Iltis, C.,Chalhoub, S.,Dejaegere, A.,Osz, J.,Rochel, N.; Advances in Vitamin D Receptor Function and Evolution Based on the 3D Structure of the Lamprey Ligand-Binding Domain.; J.Med.Chem., 65:5821-5829, 2022; PubMed: 35302785; DOI: 10.1021/acs.jmedchem.2c00171

実験手法

X-RAY DIFFRACTION (2.5 Å)