7QP4

Complex of a Gemini-cholesterol analogue with Retinoid-related Orphan Receptor gamma

Summary for 7QP4

• Entry DOI: 10.2210/pdb7qp4/pdb
• Descriptor: Nuclear receptor ROR-gamma, HIS-VAL-GLU-ARG-LEU-GLN-ILE-PHE-GLN-HIS-LEU-HIS-PRO-ILE-VAL, ACETATE ION, ... (5 entities in total)
• Functional Keywords: complex, ror, inverse agonist, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 63081.31

Authors

Rochel, N. (deposition date: 2022-01-02, release date: 2022-12-14, Last modification date: 2024-01-31)

• Primary citation: Gomez-Bouzo, U.,Fall, A.,Osz, J.,Fall, Y.,Rochel, N.,Santalla, H.; Development of novel Gemini-cholesterol analogues for retinoid-related orphan receptors; Org Chem Front, 9:1522-1530, 2022; DOI: 10.1039/D2QO00040G

Experimental method

X-RAY DIFFRACTION (2.3 Å)