7QP4
Complex of a Gemini-cholesterol analogue with Retinoid-related Orphan Receptor gamma
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Nuclear receptor ROR-gamma | polymer | 259 | 30014.7 | 2 | UniProt (P51449) Pfam (PF00104) | Homo sapiens (human) | Nuclear receptor RZR-gamma,Nuclear receptor subfamily 1 group F member 3,RAR-related orphan receptor C,Retinoid-related orphan receptor-gamma |
| 2 | C (P) | HIS-VAL-GLU-ARG-LEU-GLN-ILE-PHE-GLN-HIS-LEU-HIS-PRO-ILE-VAL | polymer | 15 | 1870.2 | 1 | UniProt (by SIFTS) (P51449) | Homo sapiens (Human) | |
| 3 | D, E, G, H (A, B) | ACETATE ION | non-polymer | 59.0 | 4 | Chemie (ACT) | |||
| 4 | F, I (A, B) | (3~{S},8~{S},9~{S},10~{R},13~{R},14~{S},17~{R})-17-[(6~{R})-2,10-dimethyl-2-oxidanyl-undecan-6-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1~{H}-cyclopenta[a]phenanthren-3-ol | non-polymer | 472.8 | 2 | Chemie (ECK) | |||
| 5 | J, K, L (A, B, P) | water | water | 18.0 | 194 | Chemie (HOH) |
Sequence modifications
A, B: 264 - 518 (UniProt: P51449)
| PDB | External Database | Details |
|---|---|---|
| Gly 260 | - | expression tag |
| Ser 261 | - | expression tag |
| His 262 | - | expression tag |
| Met 263 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61899.6 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1181.7 | |
| All* | Total formula weight | 63081.3 |
