7QK8

Crystal structure of the ALDH1A3-NAD+ complex

Summary for 7QK8

Entry DOI	10.2210/pdb7qk8/pdb
Descriptor	Aldehyde dehydrogenase family 1 member A3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, DI(HYDROXYETHYL)ETHER, ... (7 entities in total)
Functional Keywords	aldh1a3, aldehyde dehydrogenase family 1 member a3, nad+, oxidoreductase
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	119485.79
Authors	Castellvi, A.,Farres, J. (deposition date: 2021-12-17, release date: 2022-04-20, Last modification date: 2024-01-31)
Primary citation	Castellvi, A.,Pequerul, R.,Barracco, V.,Juanhuix, J.,Pares, X.,Farres, J. Structural and biochemical evidence that ATP inhibits the cancer biomarker human aldehyde dehydrogenase 1A3. Commun Biol, 5:354-354, 2022 Cited by PubMed: 35418200 DOI: 10.1038/s42003-022-03311-1 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.893 Å)

Structure validation