7QK8
Crystal structure of the ALDH1A3-NAD+ complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Aldehyde dehydrogenase family 1 member A3 | polymer | 529 | 58186.5 | 2 | UniProt (P47895) Pfam (PF00171) | Homo sapiens (human) | Aldehyde dehydrogenase 6,Retinaldehyde dehydrogenase 3,RalDH3 |
| 2 | C, K (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 3 | D, L (A, B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 2 | Chemie (PEG) | |||
| 4 | E, F, H, I, J... (A, B) | GLYCEROL | non-polymer | 92.1 | 9 | Chemie (GOL) | |||
| 5 | G, O (A, B) | O-ACETALDEHYDYL-HEXAETHYLENE GLYCOL | non-polymer | 324.4 | 2 | Chemie (P4C) | |||
| 6 | P (B) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | S, T (A, B) | water | water | 18.0 | 593 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 512 (UniProt: P47895)
| PDB | External Database | Details |
|---|---|---|
| His -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| Leu -10 | - | expression tag |
| Glu -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Thr -7 | - | expression tag |
| Ser -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Lys -3 | - | expression tag |
| Lys -2 | - | expression tag |
| Ala -1 | - | expression tag |
| Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 116373.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3112.7 | |
| All* | Total formula weight | 119485.8 |
