7QGS

Crystal structure of p300 CH1 domain in complex with CITIF (a CITED2-HIF-1alpha hybrid)

7QGS の概要

• エントリーDOI: 10.2210/pdb7qgs/pdb
• 分子名称: Cbp/p300-interacting transactivator 2,Hypoxia-inducible factor 1-alpha, Histone acetyltransferase, ZINC ION, ... (4 entities in total)
• 機能のキーワード: hypoxia, transcription factor, intrinsically disordered protein, protein binding
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 17491.15

構造登録者

Hegedus, Z.,Wilson, A.J.,Edwards, T.A. (登録日: 2021-12-10, 公開日: 2022-05-11, 最終更新日: 2024-01-31)

• 主引用文献: Hobor, F.,Hegedus, Z.,Ibarra, A.A.,Petrovicz, V.L.,Bartlett, G.J.,Sessions, R.B.,Wilson, A.J.,Edwards, T.A.; Understanding p300-transcription factor interactions using sequence variation and hybridization.; Rsc Chem Biol, 3:592-603, 2022; PubMed: 35656479; DOI: 10.1039/d2cb00026a

実験手法

X-RAY DIFFRACTION (2 Å)