7QEW

human Connexin 26 class 2 hexamer at 90mmHg PCO2, pH7.4

Summary for 7QEW

• Entry DOI: 10.2210/pdb7qew/pdb
• EMDB information: 13943
• Descriptor: Gap junction beta-2 protein, DODECYL-BETA-D-MALTOSIDE, PHOSPHATIDYLETHANOLAMINE, ... (4 entities in total)
• Functional Keywords: gap junction, ion channel, carbon dioxide sensitive, membrane protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 6
• Total formula weight: 174141.44

Authors

Brotherton, D.H.,Cameron, A.D.,Savva, C.G.,Ragan, T.J. (deposition date: 2021-12-03, release date: 2022-03-30, Last modification date: 2022-05-18)

• Primary citation: Brotherton, D.H.,Savva, C.G.,Ragan, T.J.,Dale, N.,Cameron, A.D.; Conformational changes and CO 2 -induced channel gating in connexin26.; Structure, 30:697-, 2022; PubMed: 35276081; DOI: 10.1016/j.str.2022.02.010

Experimental method

ELECTRON MICROSCOPY (2.1 Å)