7QBT

B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound.

Summary for 7QBT

Entry DOI	10.2210/pdb7qbt/pdb
Related	7QBS 7QBU 7QBV
Descriptor	Methyl coenzyme M reductase-arginine methyltransferase Mmp10, IRON/SULFUR CLUSTER, FE (III) ION, ... (7 entities in total)
Functional Keywords	radical sam, b12 binding, methyltransferase, sp3 carbon methylation, metal binding protein
Biological source	Methanosarcina acetivorans
Total number of polymer chains	4
Total formula weight	200148.20
Authors	Fyfe, C.D.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O. (deposition date: 2021-11-19, release date: 2022-02-02, Last modification date: 2024-01-31)
Primary citation	Fyfe, C.D.,Bernardo-Garcia, N.,Fradale, L.,Grimaldi, S.,Guillot, A.,Brewee, C.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O. Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase. Nature, 602:336-342, 2022 Cited by PubMed: 35110733 DOI: 10.1038/s41586-021-04355-9 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation