7QBT

B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Methyl coenzyme M reductase-arginine methyltransferase Mmp10	polymer	436	47964.9	4	UniProt (A0A832SFM5) Pfam (PF19238) UniProt (by SIFTS) (Q8THG6)	Methanosarcina acetivorans
2	E, J, O, T (A, B, C, D)	IRON/SULFUR CLUSTER	non-polymer		351.6	4	Chemie (SF4)
3	F, K, P, U (A, B, C, D)	FE (III) ION	non-polymer		55.8	4	Chemie (FE)
4	G, L, Q, V (A, B, C, D)	5'-DEOXY-5'-METHYLTHIOADENOSINE	non-polymer		297.3	4	Chemie (MTA)
5	H, M, R, W (A, B, C, D)	CO-METHYLCOBALAMIN	non-polymer		1344.4	4	Chemie (COB)
6	I, N, S, X (A, B, C, D)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
7	AA, BA, Y, Z (C, D, A, B)	water	water		18.0	1268	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 411 (UniProt: A0A832SFM5)

PDB	External Database	Details
Met -24	-	initiating methionine
Ala -23	-	expression tag
Ser -22	-	expression tag
Trp -21	-	expression tag
Ser -20	-	expression tag
His -19	-	expression tag
Pro -18	-	expression tag
Gln -17	-	expression tag
Phe -16	-	expression tag
Glu -15	-	expression tag
Lys -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Gly -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Gly -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	191859.4
Non-Polymers*	Number of molecules	20
	Total formula weight	8288.8
All*	Total formula weight	200148.2

*Water molecules are not included.