7QBT

B12-dependent radical SAM methyltransferase, Mmp10 with [4Fe-4S] cluster, cobalamin, and S-methyl-5'-thioadenosine bound.

7QBT の概要

• エントリーDOI: 10.2210/pdb7qbt/pdb
• 関連するPDBエントリー: 7QBS 7QBU 7QBV
• 分子名称: Methyl coenzyme M reductase-arginine methyltransferase Mmp10, IRON/SULFUR CLUSTER, FE (III) ION, ... (7 entities in total)
• 機能のキーワード: radical sam, b12 binding, methyltransferase, sp3 carbon methylation, metal binding protein
• 由来する生物種: Methanosarcina acetivorans
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 200148.20

構造登録者

Fyfe, C.D.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O. (登録日: 2021-11-19, 公開日: 2022-02-02, 最終更新日: 2024-01-31)

• 主引用文献: Fyfe, C.D.,Bernardo-Garcia, N.,Fradale, L.,Grimaldi, S.,Guillot, A.,Brewee, C.,Chavas, L.M.G.,Legrand, P.,Benjdia, A.,Berteau, O.; Crystallographic snapshots of a B 12 -dependent radical SAM methyltransferase.; Nature, 602:336-342, 2022; PubMed: 35110733; DOI: 10.1038/s41586-021-04355-9

実験手法

X-RAY DIFFRACTION (1.9 Å)