7Q9B

MHC Class I A02 Allele presenting EAAGIGILTV, in complex with Mel8 TCR

This is a non-PDB format compatible entry.

Summary for 7Q9B

• Entry DOI: 10.2210/pdb7q9b/pdb
• Descriptor: MHC class I antigen, Beta-2-microglobulin, GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL, ... (7 entities in total)
• Functional Keywords: melanoma epitope, autoimmunity, immune system
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 10
• Total formula weight: 187425.63

Authors

Rizkallah, P.J.,Sewell, A.K.,Wall, A.,Fuller, A. (deposition date: 2021-11-12, release date: 2023-02-22, Last modification date: 2024-02-07)

• Primary citation: Dolton, G.,Rius, C.,Wall, A.,Szomolay, B.,Bianchi, V.,Galloway, S.A.E.,Hasan, M.S.,Morin, T.,Caillaud, M.E.,Thomas, H.L.,Theaker, S.,Tan, L.R.,Fuller, A.,Topley, K.,Legut, M.,Attaf, M.,Hopkins, J.R.,Behiry, E.,Zabkiewicz, J.,Alvares, C.,Lloyd, A.,Rogers, A.,Henley, P.,Fegan, C.,Ottmann, O.,Man, S.,Crowther, M.D.,Donia, M.,Svane, I.M.,Cole, D.K.,Brown, P.E.,Rizkallah, P.,Sewell, A.K.; Targeting of multiple tumor-associated antigens by individual T cell receptors during successful cancer immunotherapy.; Cell, 186:3333-3349.e27, 2023; PubMed: 37490916; DOI: 10.1016/j.cell.2023.06.020

Experimental method

X-RAY DIFFRACTION (3.24 Å)