7Q5U

The tandem SH2 domains of SYK with a bound CD3G diphospho-ITAM peptide

This is a non-PDB format compatible entry.

Summary for 7Q5U

• Entry DOI: 10.2210/pdb7q5u/pdb
• Descriptor: Tyrosine-protein kinase SYK, T-cell surface glycoprotein CD3 gamma chain, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: signalling, kinase, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 12
• Total formula weight: 196170.33

Authors

Bradshaw, W.J.,Katis, V.L.,Chen, Z.,Bountra, C.,von Delft, F.,Gileadi, O.,Brennan, P.E. (deposition date: 2021-11-04, release date: 2021-11-24, Last modification date: 2024-01-31)

• Primary citation: Bradshaw, W.J.,Katis, V.L.,Chen, Z.,Bountra, C.,von Delft, F.,Gileadi, O.,Brennan, P.E.; The tandem SH2 domains of SYK; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)