7Q5U
The tandem SH2 domains of SYK with a bound CD3G diphospho-ITAM peptide
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (AAA, BBB, CCC, DDD, EEE...) | Tyrosine-protein kinase SYK | polymer | 265 | 29907.0 | 6 | UniProt (P43405) Pfam (PF00017) | Homo sapiens (Human) | Spleen tyrosine kinase,p72-Syk |
| 2 | G, H, I, J, K... (GGG, HHH, III, JJJ, KKK...) | T-cell surface glycoprotein CD3 gamma chain | polymer | 20 | 2611.5 | 6 | UniProt (P09693) Pfam (PF02189) | Homo sapiens | T-cell receptor T3 gamma chain |
| 3 | M, N, R, S, T (AAA, CCC, DDD) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 4 | O, Q, U, W (AAA, BBB, EEE, FFF) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 4 | Chemie (PEG) | |||
| 5 | P, V (AAA, EEE) | 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE | non-polymer | 162.2 | 2 | Chemie (P4G) | |||
| 6 | AA, BA, CA, DA, EA... (DDD, EEE, FFF, GGG, HHH...) | water | water | 18.0 | 613 | Chemie (HOH) |
Sequence modifications
AAA, BBB, CCC, DDD, EEE, FFF: 6 - 269 (UniProt: P43405)
| PDB | External Database | Details |
|---|---|---|
| Ser 5 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 195111.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1059.3 | |
| All* | Total formula weight | 196170.3 |
