7Q5U

The tandem SH2 domains of SYK with a bound CD3G diphospho-ITAM peptide

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
BBB	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
CCC	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
DDD	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
EEE	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
FFF	0004715	molecular_function	non-membrane spanning protein tyrosine kinase activity
GGG	0004888	molecular_function	transmembrane signaling receptor activity
GGG	0007166	biological_process	cell surface receptor signaling pathway
GGG	0016020	cellular_component	membrane
HHH	0004888	molecular_function	transmembrane signaling receptor activity
HHH	0007166	biological_process	cell surface receptor signaling pathway
HHH	0016020	cellular_component	membrane
III	0004888	molecular_function	transmembrane signaling receptor activity
III	0007166	biological_process	cell surface receptor signaling pathway
III	0016020	cellular_component	membrane
JJJ	0004888	molecular_function	transmembrane signaling receptor activity
JJJ	0007166	biological_process	cell surface receptor signaling pathway
JJJ	0016020	cellular_component	membrane
KKK	0004888	molecular_function	transmembrane signaling receptor activity
KKK	0007166	biological_process	cell surface receptor signaling pathway
KKK	0016020	cellular_component	membrane
LLL	0004888	molecular_function	transmembrane signaling receptor activity
LLL	0007166	biological_process	cell surface receptor signaling pathway
LLL	0016020	cellular_component	membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:21469132, ECO:0007744|PubMed:19690332

Chain	Residue	Details
AAA	TYR28
BBB	TYR28
CCC	TYR28
DDD	TYR28
EEE	TYR28
FFF	TYR28

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site_id	SWS_FT_FI2
Number of Residues	12
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:21469132

Chain	Residue	Details
AAA	SER44
EEE	SER202
FFF	SER44
FFF	SER202
AAA	SER202
BBB	SER44
BBB	SER202
CCC	SER44
CCC	SER202
DDD	SER44
DDD	SER202
EEE	SER44

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	MOD_RES: Phosphotyrosine => ECO:0000269|PubMed:21469132

Chain	Residue	Details
AAA	TYR47
EEE	TYR131
FFF	TYR47
FFF	TYR131
AAA	TYR131
BBB	TYR47
BBB	TYR131
CCC	TYR47
CCC	TYR131
DDD	TYR47
DDD	TYR131
EEE	TYR47

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	MOD_RES: Phosphothreonine => ECO:0000269|PubMed:21469132

Chain	Residue	Details
AAA	THR256
BBB	THR256
CCC	THR256
DDD	THR256
EEE	THR256
FFF	THR256

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