7Q4Q

Magacizumab Fab fragment in complex with human LRG1 epitope

Summary for 7Q4Q

Entry DOI	10.2210/pdb7q4q/pdb
Descriptor	Magacizumab light chain, Magacizumab heavy chain, LRG1 epitope, ... (5 entities in total)
Functional Keywords	antibody, cancer, angiogenesis, human, immune system
Biological source	Mus musculus More
Total number of polymer chains	6
Total formula weight	98470.00
Authors	Gutierrez-Fernandez, J.,Luecke, H. (deposition date: 2021-11-01, release date: 2022-06-15, Last modification date: 2024-01-31)
Primary citation	Gutierrez-Fernandez, J.,Javaid, F.,De Rossi, G.,Chudasama, V.,Greenwood, J.,Moss, S.E.,Luecke, H. Structural basis of human LRG1 recognition by Magacizumab, a humanized monoclonal antibody with therapeutic potential. Acta Crystallogr D Struct Biol, 78:725-734, 2022 Cited by PubMed: 35647920 DOI: 10.1107/S2059798322004132 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.65 Å)

Structure validation