7Q4Q
Magacizumab Fab fragment in complex with human LRG1 epitope
Summary for 7Q4Q
Entry DOI | 10.2210/pdb7q4q/pdb |
Descriptor | Magacizumab light chain, Magacizumab heavy chain, LRG1 epitope, ... (5 entities in total) |
Functional Keywords | antibody, cancer, angiogenesis, human, immune system |
Biological source | Mus musculus More |
Total number of polymer chains | 6 |
Total formula weight | 98470.00 |
Authors | Gutierrez-Fernandez, J.,Luecke, H. (deposition date: 2021-11-01, release date: 2022-06-15, Last modification date: 2024-01-31) |
Primary citation | Gutierrez-Fernandez, J.,Javaid, F.,De Rossi, G.,Chudasama, V.,Greenwood, J.,Moss, S.E.,Luecke, H. Structural basis of human LRG1 recognition by Magacizumab, a humanized monoclonal antibody with therapeutic potential. Acta Crystallogr D Struct Biol, 78:725-734, 2022 Cited by PubMed: 35647920DOI: 10.1107/S2059798322004132 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.65 Å) |
Structure validation
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