7Q4I

Crystal structure of DmC1GalT1 in complex with UDP-Mn2+ and the APD-TGalNAc-RP

Summary for 7Q4I

Entry DOI	10.2210/pdb7q4i/pdb
Descriptor	Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, Mucin-1, URIDINE-5'-DIPHOSPHATE, ... (7 entities in total)
Functional Keywords	c1galt1, t-synthase, t antigen, tn antigen, mucin-type o-glycosylation, transferase
Biological source	Drosophila melanogaster (Fruit fly) More
Total number of polymer chains	4
Total formula weight	75389.86
Authors	Gonzalez-Ramirez, A.M.,Coelho, H.,Companon, I.,Grosso, A.S.,Yang, Z.,Narimatsu, Y.,Clausen, H.,Marcelo, F.,Corzana, F.,Hurtado-Guerrero, R. (deposition date: 2021-10-31, release date: 2022-04-13, Last modification date: 2022-11-16)
Primary citation	Gonzalez-Ramirez, A.M.,Grosso, A.S.,Yang, Z.,Companon, I.,Coelho, H.,Narimatsu, Y.,Clausen, H.,Marcelo, F.,Corzana, F.,Hurtado-Guerrero, R. Structural basis for the synthesis of the core 1 structure by C1GalT1. Nat Commun, 13:2398-2398, 2022 Cited by PubMed: 35504880 DOI: 10.1038/s41467-022-29833-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation