7Q4I
Crystal structure of DmC1GalT1 in complex with UDP-Mn2+ and the APD-TGalNAc-RP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | polymer | 316 | 36265.8 | 2 | UniProt (Q7K237) Pfam (PF02434) | Drosophila melanogaster (Fruit fly) | Core 1 O-glycan T-synthase,Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1,Core 1 beta1,C1GalT1,Core 1 beta3-Gal-T1 |
| 2 | C, D (G, F) | Mucin-1 | polymer | 6 | 655.7 | 2 | UniProt (P15941) | Homo sapiens | MUC-1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,CA 15-3,Carcinoma-associated mucin,Episialin,H23AG,Krebs von den Lungen-6,KL-6,PEMT,Peanut-reactive urinary mucin,PUM,Polymorphic epithelial mucin,PEM,Tumor-associated epithelial membrane antigen,EMA,Tumor-associated mucin |
| 3 | E, H (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (3084486) PubChem (6101632) PubChem (6604175) PubChem (11811538) PubChem (12049241) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (57448939) PubChem (53486216) PubChem (60098857) PubChem (91746160) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) | |||
| 4 | F, I, L (A, B, F) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, J (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) PubChem (27854) | |||
| 6 | K, M (G, F) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 2 | Chemie (A2G) | |||
| 7 | N, O, P (A, B, F) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73843.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1546.8 | |
| All* | Total formula weight | 75389.9 |
