7Q4I
Crystal structure of DmC1GalT1 in complex with UDP-Mn2+ and the APD-TGalNAc-RP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | polymer | 316 | 36265.8 | 2 | UniProt (Q7K237) Pfam (PF02434) | Drosophila melanogaster (Fruit fly) | Core 1 O-glycan T-synthase,Core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1,Core 1 beta1,C1GalT1,Core 1 beta3-Gal-T1 |
| 2 | C, D (G, F) | Mucin-1 | polymer | 6 | 655.7 | 2 | UniProt (P15941) | Homo sapiens | MUC-1,Breast carcinoma-associated antigen DF3,Cancer antigen 15-3,CA 15-3,Carcinoma-associated mucin,Episialin,H23AG,Krebs von den Lungen-6,KL-6,PEMT,Peanut-reactive urinary mucin,PUM,Polymorphic epithelial mucin,PEM,Tumor-associated epithelial membrane antigen,EMA,Tumor-associated mucin |
| 3 | E, H (A, B) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 2 | Chemie (UDP) | |||
| 4 | F, I, L (A, B, F) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 5 | G, J (A, B) | MANGANESE (II) ION | non-polymer | 54.9 | 2 | Chemie (MN) | |||
| 6 | K, M (G, F) | 2-acetamido-2-deoxy-alpha-D-galactopyranose | non-polymer | 221.2 | 2 | Chemie (A2G) | |||
| 7 | N, O, P (A, B, F) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 73843.0 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1546.8 | |
| All* | Total formula weight | 75389.9 |
