7Q3B
Crystal structure of human STING in complex with 3'3'-c-(2'F,2'dA-isonucA)MP
Summary for 7Q3B
Entry DOI | 10.2210/pdb7q3b/pdb |
Descriptor | Stimulator of interferon genes protein, 3'3'-c-(2'F,2'dA-isonucA)MP (3 entities in total) |
Functional Keywords | sting, antiviral, activator, immune system |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 23833.47 |
Authors | |
Primary citation | Dejmek, M.,Sala, M.,Brazdova, A.,Vanekova, L.,Smola, M.,Klima, M.,Brehova, P.,Budesinsky, M.,Dracinsky, M.,Prochazkova, E.,Zavrel, M.,Simak, O.,Pav, O.,Boura, E.,Birkus, G.,Nencka, R. Discovery of isonucleotidic CDNs as potent STING agonists with immunomodulatory potential. Structure, 30:1146-, 2022 Cited by PubMed: 35690061DOI: 10.1016/j.str.2022.05.012 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.55733924728 Å) |
Structure validation
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