7Q3B
Crystal structure of human STING in complex with 3'3'-c-(2'F,2'dA-isonucA)MP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Stimulator of interferon genes protein | polymer | 204 | 23189.1 | 1 | UniProt (Q86WV6) Pfam (PF15009) | Homo sapiens (human) | hSTING,Endoplasmic reticulum interferon stimulator,ERIS,Mediator of IRF3 activation,hMITA,Transmembrane protein 173 |
| 2 | B (A) | 3'3'-c-(2'F,2'dA-isonucA)MP | non-polymer | 644.4 | 1 | Chemie (8SC) | |||
| 3 | C (A) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A: 140 - 343 (UniProt: Q86WV6)
| PDB | External Database | Details |
|---|---|---|
| Arg 232 | His 232 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23189.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 644.4 | |
| All* | Total formula weight | 23833.5 |
