7Q12

Human GYS1-GYG1 complex activated state bound to glucose-6-phosphate

Summary for 7Q12

• Entry DOI: 10.2210/pdb7q12/pdb
• Related: 7Q0B 7Q0S
• EMDB information: 13743 13751 13752
• Descriptor: Glycogen [starch] synthase, muscle, Glycogenin-1, 6-O-phosphono-alpha-D-glucopyranose (3 entities in total)
• Functional Keywords: glycogen, complex, phosphorylation, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 494272.75

Authors

McCorvie, T.J.,Shrestha, L.,Froese, D.S.,Ferreira, I.M.,Yue, W.W. (deposition date: 2021-10-17, release date: 2022-07-27)

• Primary citation: McCorvie, T.J.,Loria, P.M.,Tu, M.,Han, S.,Shrestha, L.,Froese, D.S.,Ferreira, I.M.,Berg, A.P.,Yue, W.W.; Molecular basis for the regulation of human glycogen synthase by phosphorylation and glucose-6-phosphate.; Nat.Struct.Mol.Biol., 29:628-638, 2022; PubMed: 35835870; DOI: 10.1038/s41594-022-00799-3

Experimental method

ELECTRON MICROSCOPY (3.7 Å)