7PUX

Structure of p97 N-D1(L198W) in complex with Fragment TROLL2

Summary for 7PUX

• Entry DOI: 10.2210/pdb7pux/pdb
• Descriptor: Transitional endoplasmic reticulum ATPase, ADENOSINE-5'-DIPHOSPHATE, FORMIC ACID, ... (7 entities in total)
• Functional Keywords: hydrolase, p97, vcp, fragment screening
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 53897.66

Authors

Bothe, S.,Schindelin, H. (deposition date: 2021-10-01, release date: 2022-12-14, Last modification date: 2024-01-31)

• Primary citation: Bothe, S.,Hanzelmann, P.,Bohler, S.,Kehrein, J.,Zehe, M.,Wiedemann, C.,Hellmich, U.A.,Brenk, R.,Schindelin, H.,Sotriffer, C.; Fragment screening using biolayer interferometry reveals ligands targeting the SHP-motif binding site of the AAA+ ATPase p97; Commun Chem, 5:169-, 2022; DOI: 10.1038/s42004-022-00782-5

Experimental method

X-RAY DIFFRACTION (1.73 Å)