7PUX

Structure of p97 N-D1(L198W) in complex with Fragment TROLL2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Transitional endoplasmic reticulum ATPase	polymer	468	52388.9	1	UniProt (P55072) Pfam (PF02359) Pfam (PF02933) Pfam (PF00004) Pfam (PF17862) In PDB	Homo sapiens (Human)	TER ATPase,15S Mg(2+)-ATPase p97 subunit,Valosin-containing protein,VCP
2	A	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	1	Chemie (ADP)
3	A	FORMIC ACID	non-polymer		46.0	16	Chemie (FMT)
4	A	(1S)-2-amino-1-(4-bromophenyl)ethan-1-ol	non-polymer		216.1	1	Chemie (6LY)
5	A	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
7		water	water		18.0	255	Chemie (HOH)

Sequence modifications

A: 1 - 460 (UniProt: P55072)

PDB	External Database	Details
Trp 198	Leu 198	engineered mutation
Arg 461	-	expression tag
Ser 462	-	expression tag
His 463	-	expression tag
His 464	-	expression tag
His 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	52388.9
Non-Polymers*	Number of molecules	20
	Total formula weight	1508.8
All*	Total formula weight	53897.7

*Water molecules are not included.