7POL
Crystal structure of profragilysin-3 (proBFT-3) from Bacteroides fragilis in complex with flumequine
Summary for 7POL
Entry DOI | 10.2210/pdb7pol/pdb |
Related | 7PND |
Descriptor | BFT-3, ZINC ION, (12~{R})-7-fluoranyl-12-methyl-4-oxidanylidene-1-azatricyclo[7.3.1.0^{5,13}]trideca-2,5(13),6,8-tetraene-3-carboxylic acid, ... (7 entities in total) |
Functional Keywords | protease, zymogen, proteolysis, enterotoxin, fragilysin, hydrolase |
Biological source | Bacteroides fragilis |
Total number of polymer chains | 2 |
Total formula weight | 92389.24 |
Authors | Eckhard, U.,Guevara, T.,Gomis-Ruth, F.X. (deposition date: 2021-09-09, release date: 2022-09-14, Last modification date: 2024-01-31) |
Primary citation | Jimenez-Alesanco, A.,Eckhard, U.,Asencio Del Rio, M.,Vega, S.,Guevara, T.,Velazquez-Campoy, A.,Gomis-Ruth, F.X.,Abian, O. Repositioning small molecule drugs as allosteric inhibitors of the BFT-3 toxin from enterotoxigenic Bacteroides fragilis. Protein Sci., 31:e4427-e4427, 2022 Cited by PubMed: 36173175DOI: 10.1002/pro.4427 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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