7PLF

Human Carbonic Anhydrase I in complex with clorsulon

This is a non-PDB format compatible entry.

Summary for 7PLF

• Entry DOI: 10.2210/pdb7plf/pdb
• Descriptor: Carbonic anhydrase 1, ZINC ION, 4-azanyl-6-[1,2,2-tris(chloranyl)ethenyl]benzene-1,3-disulfonamide, ... (4 entities in total)
• Functional Keywords: carbonic anhydrase i, clorsulon, inhibitor, sulfonamide, metalloenzyme, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 58704.50

Authors

Angeli, A.,Ferraroni, M. (deposition date: 2021-08-31, release date: 2022-09-07, Last modification date: 2024-02-07)

• Primary citation: Ferraroni, M.,Angeli, A.,Carradori, S.,Supuran, C.T.; Inhibition of Schistosoma mansoni carbonic anhydrase by the antiparasitic drug clorsulon: X-ray crystallographic and in vitro studies.; Acta Crystallogr D Struct Biol, 78:321-327, 2022; PubMed: 35234146; DOI: 10.1107/S2059798322000079

Experimental method

X-RAY DIFFRACTION (1.461 Å)