7PI4
FAK Protac GSK215 in complex with FAK and pVHL:ElonginC:ElonginB
This is a non-PDB format compatible entry.
Summary for 7PI4
Entry DOI | 10.2210/pdb7pi4/pdb |
Descriptor | von Hippel-Lindau disease tumor suppressor, Elongin-B, Isoform 2 of Elongin-C, ... (9 entities in total) |
Functional Keywords | transferase, protac |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 74404.45 |
Authors | Chung, C. (deposition date: 2021-08-19, release date: 2021-09-29, Last modification date: 2024-01-31) |
Primary citation | Law, R.P.,Nunes, J.,Chung, C.W.,Bantscheff, M.,Buda, K.,Dai, H.,Evans, J.P.,Flinders, A.,Klimaszewska, D.,Lewis, A.J.,Muelbaier, M.,Scott-Stevens, P.,Stacey, P.,Tame, C.J.,Watt, G.F.,Zinn, N.,Queisser, M.A.,Harling, J.D.,Benowitz, A.B. Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs. Angew.Chem.Int.Ed.Engl., 60:23327-23334, 2021 Cited by PubMed: 34416073DOI: 10.1002/anie.202109237 PDB entries with the same primary citation |
Experimental method |
Structure validation
Download full validation report