7P79

SARS-CoV-2 spike protein in complex with sybodyb#15 in a 1up/1up-out/1down conformation.

7P79 の概要

• エントリーDOI: 10.2210/pdb7p79/pdb
• 関連するPDBエントリー: 7P77 7P78 7P7A 7P7B
• EMDBエントリー: 12084
• 分子名称: Spike glycoprotein, sybody#15, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (7 entities in total)
• 機能のキーワード: sars-cov-2 spike protein sybody, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 476513.26

構造登録者

Walter, J.D.,Hutter, C.A.J.,Garaeva, A.A.,Scherer, M.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Huerlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A. (登録日: 2021-07-19, 公開日: 2021-08-04, 最終更新日: 2022-04-20)

• 主引用文献: Walter, J.D.,Scherer, M.,Hutter, C.A.J.,Garaeva, A.A.,Zimmermann, I.,Wyss, M.,Rheinberger, J.,Ruedin, Y.,Earp, J.C.,Egloff, P.,Sorgenfrei, M.,Hurlimann, L.M.,Gonda, I.,Meier, G.,Remm, S.,Thavarasah, S.,van Geest, G.,Bruggmann, R.,Zimmer, G.,Slotboom, D.J.,Paulino, C.,Plattet, P.,Seeger, M.A.; Biparatopic sybodies neutralize SARS-CoV-2 variants of concern and mitigate drug resistance.; Embo Rep., 23:e54199-e54199, 2022; PubMed: 35253970; DOI: 10.15252/embr.202154199

実験手法

ELECTRON MICROSCOPY (4 Å)