7P65

Progressive supranuclear palsy tau filament

Summary for 7P65

• Entry DOI: 10.2210/pdb7p65/pdb
• EMDB information: 13218
• Descriptor: Microtubule-associated protein tau (1 entity in total)
• Functional Keywords: amyloid fibril, protein fibril
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 5
• Total formula weight: 229599.35

Authors

Shi, Y.,Zhang, W.,Yang, Y.,Murzin, A.G.,Falcon, B.,Kotecha, A.,van Beers, M.,Tarutani, A.,Kametani, F.,Garringer, H.J.,Vidal, R.,Hallinan, G.I.,Lashley, T.,Saito, Y.,Murayama, S.,Yoshida, M.,Tanaka, H.,Kakita, A.,Ikeuchi, T.,Robinson, A.C.,Mann, D.M.A.,Kovacs, G.G.,Revesz, T.,Ghetti, B.,Hasegawa, M.,Goedert, M.,Scheres, S.H.W. (deposition date: 2021-07-15, release date: 2021-09-15, Last modification date: 2021-10-27)

• Primary citation: Shi, Y.,Zhang, W.,Yang, Y.,Murzin, A.G.,Falcon, B.,Kotecha, A.,van Beers, M.,Tarutani, A.,Kametani, F.,Garringer, H.J.,Vidal, R.,Hallinan, G.I.,Lashley, T.,Saito, Y.,Murayama, S.,Yoshida, M.,Tanaka, H.,Kakita, A.,Ikeuchi, T.,Robinson, A.C.,Mann, D.M.A.,Kovacs, G.G.,Revesz, T.,Ghetti, B.,Hasegawa, M.,Goedert, M.,Scheres, S.H.W.; Structure-based classification of tauopathies.; Nature, 598:359-363, 2021; PubMed: 34588692; DOI: 10.1038/s41586-021-03911-7

Experimental method

ELECTRON MICROSCOPY (2.7 Å)