7P47

Structure of the E3 ligase Smc5/Nse2 in complex with Ubc9-SUMO thioester mimetic

Summary for 7P47

• Entry DOI: 10.2210/pdb7p47/pdb
• Descriptor: Structural maintenance of chromosomes protein 5, SUMO-conjugating enzyme UBC9, E3 SUMO-protein ligase MMS21, ... (5 entities in total)
• Functional Keywords: sumo e3 ligase activity, dna repair, ligase
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 5
• Total formula weight: 80711.56

Authors

Lascorz, J.,Varejao, N.,Reverter, D. (deposition date: 2021-07-09, release date: 2021-11-24, Last modification date: 2024-01-31)

• Primary citation: Varejao, N.,Lascorz, J.,Codina-Fabra, J.,Belli, G.,Borras-Gas, H.,Torres-Rosell, J.,Reverter, D.; Structural basis for the E3 ligase activity enhancement of yeast Nse2 by SUMO-interacting motifs.; Nat Commun, 12:7013-7013, 2021; PubMed: 34853311; DOI: 10.1038/s41467-021-27301-9

Experimental method

X-RAY DIFFRACTION (3.314 Å)