7P1A

Carbonic Anhydrase VII Sultam Based Inhibitors

Summary for 7P1A

• Entry DOI: 10.2210/pdb7p1a/pdb
• Descriptor: Carbonic anhydrase 7, ZINC ION, GLYCEROL, ... (5 entities in total)
• Functional Keywords: carbonic anhydrase vii, inhibitor, lyase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 31506.75

Authors

D'Ambrosio, K.,De Simone, G. (deposition date: 2021-07-01, release date: 2021-11-17)

• Primary citation: Akgul, O.,Lucarini, E.,Mannelli, L.D.C.,Ghelardini, C.,D'Ambrosio, K.,Buonanno, M.,Monti, S.M.,De Simone, G.,Angeli, A.,Supuran, C.T.,Carta, F.; Sultam based Carbonic Anhydrase VII inhibitors for the management of neuropathic pain.; Eur.J.Med.Chem., 227:113956-113956, 2021; PubMed: 34731762; DOI: 10.1016/j.ejmech.2021.113956

Experimental method

X-RAY DIFFRACTION (1.58 Å)