7P0E
Crystal structure of human filamin C domains 14-15 cardiovascular disease causing mutation G1676R
Summary for 7P0E
Entry DOI | 10.2210/pdb7p0e/pdb |
Descriptor | Isoform 2 of Filamin-C, GLYCEROL, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | ig-like, mechanosensing, muscle protein, heart, structural protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 43592.78 |
Authors | Mlynek, G.,Djinovic-Carugo, K. (deposition date: 2021-06-29, release date: 2022-07-13, Last modification date: 2024-01-31) |
Primary citation | Mlynek, G.,Djinovic-Carugo, K. Analysis and prediction of pathogenic missense variants in human filamin C To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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