7P0E

Crystal structure of human filamin C domains 14-15 cardiovascular disease causing mutation G1676R

Summary for 7P0E

• Entry DOI: 10.2210/pdb7p0e/pdb
• Descriptor: Isoform 2 of Filamin-C, GLYCEROL, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: ig-like, mechanosensing, muscle protein, heart, structural protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 43592.78

Authors

Mlynek, G.,Djinovic-Carugo, K. (deposition date: 2021-06-29, release date: 2022-07-13, Last modification date: 2024-10-23)

• Primary citation: Mlynek, G.,Djinovic-Carugo, K.; Analysis and prediction of pathogenic missense variants in human filamin C; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)