7OUB
High resolution structure of Alpha-1-acid glycoprotein bound to potent anti-tumour compound UCN-01
Summary for 7OUB
Entry DOI | 10.2210/pdb7oub/pdb |
Descriptor | Alpha-1-acid glycoprotein 2, 7-HYDROXYSTAUROSPORINE (3 entities in total) |
Functional Keywords | agp2, orm2, lipocalin, complex, alpha-1-acid glycoprotein, ucn-01, protein transport |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 23026.76 |
Authors | Landin, E.J.B.,Williams, C.,Crump, M.P. (deposition date: 2021-06-11, release date: 2021-12-01, Last modification date: 2024-01-31) |
Primary citation | Landin, E.J.B.,Williams, C.,Ryan, S.A.,Bochel, A.,Akter, N.,Redfield, C.,Sessions, R.B.,Dedi, N.,Taylor, R.J.,Crump, M.P. The structural basis for high affinity binding of alpha 1-acid glycoprotein to the potent antitumor compound UCN-01. J.Biol.Chem., 297:101392-101392, 2021 Cited by PubMed: 34758357DOI: 10.1016/j.jbc.2021.101392 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.82 Å) |
Structure validation
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