7OUB

High resolution structure of Alpha-1-acid glycoprotein bound to potent anti-tumour compound UCN-01

7OUB の概要

• エントリーDOI: 10.2210/pdb7oub/pdb
• 分子名称: Alpha-1-acid glycoprotein 2, 7-HYDROXYSTAUROSPORINE (3 entities in total)
• 機能のキーワード: agp2, orm2, lipocalin, complex, alpha-1-acid glycoprotein, ucn-01, protein transport
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23026.76

構造登録者

Landin, E.J.B.,Williams, C.,Crump, M.P. (登録日: 2021-06-11, 公開日: 2021-12-01, 最終更新日: 2024-01-31)

• 主引用文献: Landin, E.J.B.,Williams, C.,Ryan, S.A.,Bochel, A.,Akter, N.,Redfield, C.,Sessions, R.B.,Dedi, N.,Taylor, R.J.,Crump, M.P.; The structural basis for high affinity binding of alpha 1-acid glycoprotein to the potent antitumor compound UCN-01.; J.Biol.Chem., 297:101392-101392, 2021; PubMed: 34758357; DOI: 10.1016/j.jbc.2021.101392

実験手法

X-RAY DIFFRACTION (1.82 Å)