7OKQ
Cryo-EM Structure of the DDB1-DCAF1-CUL4A-RBX1 Complex
Summary for 7OKQ
Entry DOI | 10.2210/pdb7okq/pdb |
EMDB information | 12964 |
Descriptor | DNA damage-binding protein 1, DDB1- and CUL4-associated factor 1, Cullin-4A, ... (4 entities in total) |
Functional Keywords | ubiquitin, e3, protein degradation, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 16 |
Total formula weight | 1603496.27 |
Authors | Mohamed, W.I.,Schenk, A.D.,Kempf, G.,Cavadini, S.,Thoma, N.H. (deposition date: 2021-05-18, release date: 2021-10-13, Last modification date: 2024-07-10) |
Primary citation | Mohamed, W.I.,Schenk, A.D.,Kempf, G.,Cavadini, S.,Basters, A.,Potenza, A.,Abdul Rahman, W.,Rabl, J.,Reichermeier, K.,Thoma, N.H. The CRL4 DCAF1 cullin-RING ubiquitin ligase is activated following a switch in oligomerization state. Embo J., 40:e108008-e108008, 2021 Cited by PubMed: 34595758DOI: 10.15252/embj.2021108008 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (8.4 Å) |
Structure validation
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