7OIX

Structure of thermostable human MFSD2A in complex with thermostable human Sync2

7OIX の概要

• エントリーDOI: 10.2210/pdb7oix/pdb
• EMDBエントリー: 12935
• 分子名称: Syncytin-2, Isoform 2 of Sodium-dependent lysophosphatidylcholine symporter 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: human membrane protein, mfs transporter, human endogenous retroviral protein, syncytin, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 121405.99

構造登録者

Martinez-Molledo, M.,Reyes, N. (登録日: 2021-05-12, 公開日: 2022-06-01, 最終更新日: 2022-06-29)

• 主引用文献: Martinez-Molledo, M.,Nji, E.,Reyes, N.; Structural insights into the lysophospholipid brain uptake mechanism and its inhibition by syncytin-2.; Nat.Struct.Mol.Biol., 29:604-612, 2022; PubMed: 35710838; DOI: 10.1038/s41594-022-00786-8

実験手法

ELECTRON MICROSCOPY (3.6 Å)