7OGJ
Crystal structure of human METTL1 in complex with SAH
Summary for 7OGJ
Entry DOI | 10.2210/pdb7ogj/pdb |
Descriptor | tRNA (guanine-N(7)-)-methyltransferase, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ... (7 entities in total) |
Functional Keywords | mettl1, complex, sah, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 2 |
Total formula weight | 60302.05 |
Authors | Nai, F.,Bedi, R.K.,Caflisch, A. (deposition date: 2021-05-06, release date: 2021-05-19, Last modification date: 2023-12-20) |
Primary citation | Nai, F.,Flores Espinoza, M.P.,Invernizzi, A.,Vargas-Rosales, P.A.,Bobileva, O.,Herok, M.,Caflisch, A. Small-Molecule Inhibitors of the m7G-RNA Writer METTL1 Acs Bio Med Chem Au, 2023 Cited by DOI: 10.1021/acsbiomedchemau.3c00030PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.59 Å) |
Structure validation
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