7OFS
Structure of SARS-CoV-2 Papain-like protease PLpro in complex with 4-(2-hydroxyethyl)phenol
Summary for 7OFS
| Entry DOI | 10.2210/pdb7ofs/pdb |
| Related | 7NFV 7OFT 7OFU |
| Descriptor | Papain-like protease nsp3, ZINC ION, CHLORIDE ION, ... (7 entities in total) |
| Functional Keywords | papain-like protease sars-cov-2 hydrolase zinc binding protein, hydrolase |
| Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
| Total number of polymer chains | 1 |
| Total formula weight | 36168.50 |
| Authors | Srinivasan, V.,Werner, N.,Falke, S.,Guenther, S.,Reinke, P.,Ewert, W.,Sprenger, J.,Koua, F.,Brognaro, H.,Ullah, N.,Andaleeb, H.,Perbandt, M.,Alves Franca, B.,Schwinzer, M.,Wang, M.,Lieske, J.,Ginn, H.,Lane, T.J.,Yefanov, O.,Gelisio, L.,Hakanpaeae, J.,Saouane, S.,Tolstikova, A.,Groessler, M.,Fleckenstein, H.,Trost, F.,Wolf, M.,Lorenzen, K.,Schubert, R.,Han, H.,Schmidt, C.,Brings, L.,Galchenkova, M.,Gevorkov, Y.,Li, C.,Perk, A.,Awel, S.,Wahab, A.,Choudary, I.,Turk, D.,Hinrichs, W.,Chapman, H.N.,Meents, A.,Betzel, C. (deposition date: 2021-05-05, release date: 2021-05-12, Last modification date: 2024-01-31) |
| Primary citation | Srinivasan, V.,Brognaro, H.,Prabhu, P.R.,de Souza, E.E.,Gunther, S.,Reinke, P.Y.A.,Lane, T.J.,Ginn, H.,Han, H.,Ewert, W.,Sprenger, J.,Koua, F.H.M.,Falke, S.,Werner, N.,Andaleeb, H.,Ullah, N.,Franca, B.A.,Wang, M.,Barra, A.L.C.,Perbandt, M.,Schwinzer, M.,Schmidt, C.,Brings, L.,Lorenzen, K.,Schubert, R.,Machado, R.R.G.,Candido, E.D.,Oliveira, D.B.L.,Durigon, E.L.,Niebling, S.,Garcia, A.S.,Yefanov, O.,Lieske, J.,Gelisio, L.,Domaracky, M.,Middendorf, P.,Groessler, M.,Trost, F.,Galchenkova, M.,Mashhour, A.R.,Saouane, S.,Hakanpaa, J.,Wolf, M.,Alai, M.G.,Turk, D.,Pearson, A.R.,Chapman, H.N.,Hinrichs, W.,Wrenger, C.,Meents, A.,Betzel, C. Antiviral activity of natural phenolic compounds in complex at an allosteric site of SARS-CoV-2 papain-like protease. Commun Biol, 5:805-805, 2022 Cited by PubMed: 35953531DOI: 10.1038/s42003-022-03737-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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