7O7F

Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist

7O7F の概要

• エントリーDOI: 10.2210/pdb7o7f/pdb
• EMDBエントリー: 12746
• 分子名称: Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, C-C chemokine receptor type 5, ... (7 entities in total)
• 機能のキーワード: g protein-coupled receptor (gpcr); ccr5; ccl5/rantes; hiv entry; aids; membrane protein structure;, membrane protein, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 7
• 化学式量合計: 184436.01

構造登録者

Isaikina, P.,Tsai, C.-J.,Dietz, N.B.,Pamula, F.,Goldie, K.N.,Schertler, G.F.X.,Maier, T.,Stahlberg, H.,Deupi, X.,Grzesiek, S. (登録日: 2021-04-13, 公開日: 2021-06-30, 最終更新日: 2022-03-16)

• 主引用文献: Isaikina, P.,Tsai, C.J.,Dietz, N.,Pamula, F.,Grahl, A.,Goldie, K.N.,Guixa-Gonzalez, R.,Branco, C.,Paolini-Bertrand, M.,Calo, N.,Cerini, F.,Schertler, G.F.X.,Hartley, O.,Stahlberg, H.,Maier, T.,Deupi, X.,Grzesiek, S.; Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist.; Sci Adv, 7:-, 2021; PubMed: 34134983; DOI: 10.1126/sciadv.abg8685

実験手法

ELECTRON MICROSCOPY (3.15 Å)