7O2W
Structure of the C9orf72-SMCR8 complex
Summary for 7O2W
Entry DOI | 10.2210/pdb7o2w/pdb |
EMDB information | 12700 |
Descriptor | Ubiquitin-like protein SMT3,Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8,Guanine nucleotide exchange protein SMCR8,Maltose/maltodextrin-binding periplasmic protein (2 entities in total) |
Functional Keywords | denn domain, coiled-coil, gtpase-activating protein, protein binding |
Biological source | Saccharomyces cerevisiae S288c (Baker's yeast) More |
Total number of polymer chains | 2 |
Total formula weight | 201557.13 |
Authors | Noerpel, J.,Cavadini, S.,Schenk, A.D.,Graff-Meyer, A.,Chao, J.,Bhaskar, V. (deposition date: 2021-03-31, release date: 2021-07-21, Last modification date: 2024-07-10) |
Primary citation | Norpel, J.,Cavadini, S.,Schenk, A.D.,Graff-Meyer, A.,Hess, D.,Seebacher, J.,Chao, J.A.,Bhaskar, V. Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture. Plos Biol., 19:e3001344-e3001344, 2021 Cited by PubMed: 34297726DOI: 10.1371/journal.pbio.3001344 PDB entries with the same primary citation |
Experimental method |
Structure validation
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