7NP1

Crystal Structure of the SARS-CoV-2 Receptor Binding Domain in Complex with Antibody ION-360

Summary for 7NP1

• Entry DOI: 10.2210/pdb7np1/pdb
• Descriptor: Spike protein S1, Immunoglobulin gamma-1 heavy chain, Immunoblobulin light chain, ... (6 entities in total)
• Functional Keywords: antibody immune system, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 12
• Total formula weight: 294200.61

Authors

Hall, G.,Cowan, R.,Carr, M. (deposition date: 2021-02-26, release date: 2021-11-17, Last modification date: 2024-01-31)

• Primary citation: Bullen, G.,Galson, J.D.,Hall, G.,Villar, P.,Moreels, L.,Ledsgaard, L.,Mattiuzzo, G.,Bentley, E.M.,Masters, E.W.,Tang, D.,Millett, S.,Tongue, D.,Brown, R.,Diamantopoulos, I.,Parthiban, K.,Tebbutt, C.,Leah, R.,Chaitanya, K.,Ergueta-Carballo, S.,Pazeraitis, D.,Surade, S.B.,Ashiru, O.,Crippa, L.,Cowan, R.,Bowler, M.W.,Campbell, J.I.,Lee, W.J.,Carr, M.D.,Matthews, D.,Pfeffer, P.,Hufton, S.E.,Sawmynaden, K.,Osbourn, J.,McCafferty, J.,Karatt-Vellatt, A.; Cross-Reactive SARS-CoV-2 Neutralizing Antibodies From Deep Mining of Early Patient Responses.; Front Immunol, 12:678570-678570, 2021; PubMed: 34211469; DOI: 10.3389/fimmu.2021.678570

Experimental method

X-RAY DIFFRACTION (2.8 Å)