7NNK
Crystal structure of S116A mutant of hydroxy ketone aldolase (SwHKA) from Sphingomonas wittichii RW1 in complex with hydroxypyruvate
Summary for 7NNK
Entry DOI | 10.2210/pdb7nnk/pdb |
Related | 6R62 |
Descriptor | HpcH/HpaI aldolase, 3-HYDROXYPYRUVIC ACID, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | class ii pyruvate aldolase, metal dependent, aldol reaction, hydroxypyruvate, pyruvate, aldolase, class ii, lyase |
Biological source | Sphingomonas wittichii (strain RW1 / DSM 6014 / JCM 10273) |
Total number of polymer chains | 2 |
Total formula weight | 53689.72 |
Authors | Justo, I.,Marsden, S.R.,Hanefeld, U.,Bento, I. (deposition date: 2021-02-25, release date: 2022-11-16, Last modification date: 2024-01-31) |
Primary citation | Marsden, S.R.,Wijma, H.J.,Mohr, M.K.F.,Justo, I.,Hagedoorn, P.L.,Laustsen, J.,Jeffries, C.M.,Svergun, D.,Mestrom, L.,McMillan, D.G.G.,Bento, I.,Hanefeld, U. Substrate Induced Movement of the Metal Cofactor between Active and Resting State. Angew.Chem.Int.Ed.Engl., 61:e202213338-e202213338, 2022 Cited by PubMed: 36214476DOI: 10.1002/anie.202213338 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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