7NN0
Crystal structure of the SARS-CoV-2 helicase in complex with AMP-PNP
Summary for 7NN0
Entry DOI | 10.2210/pdb7nn0/pdb |
Descriptor | SARS-CoV-2 helicase NSP13, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ZINC ION, ... (5 entities in total) |
Functional Keywords | nsp13, helicase, sars-cov-2, hydrolase |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) |
Total number of polymer chains | 4 |
Total formula weight | 271429.22 |
Authors | Newman, J.A.,Yosaatmadja, Y.,Douangamath, A.,Bountra, C.,Gileadi, O. (deposition date: 2021-02-23, release date: 2021-03-24, Last modification date: 2024-01-31) |
Primary citation | Newman, J.A.,Douangamath, A.,Yadzani, S.,Yosaatmadja, Y.,Aimon, A.,Brandao-Neto, J.,Dunnett, L.,Gorrie-Stone, T.,Skyner, R.,Fearon, D.,Schapira, M.,von Delft, F.,Gileadi, O. Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase. Nat Commun, 12:4848-4848, 2021 Cited by PubMed: 34381037DOI: 10.1038/s41467-021-25166-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.04 Å) |
Structure validation
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