7NN0
Crystal structure of the SARS-CoV-2 helicase in complex with AMP-PNP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0004386 | molecular_function | helicase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008270 | molecular_function | zinc ion binding |
| C | 0004386 | molecular_function | helicase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008270 | molecular_function | zinc ion binding |
| D | 0004386 | molecular_function | helicase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0008270 | molecular_function | zinc ion binding |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 48 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00986, ECO:0000269|PubMed:33232691, ECO:0007744|PDB:7CYQ |
| Chain | Residue | Details |
| A | CYS5 | |
| A | CYS55 | |
| A | CYS72 | |
| A | HIS75 | |
| B | CYS5 | |
| B | CYS8 | |
| B | CYS16 | |
| B | CYS19 | |
| B | CYS26 | |
| B | CYS29 | |
| B | HIS33 | |
| A | CYS8 | |
| B | HIS39 | |
| B | CYS50 | |
| B | CYS55 | |
| B | CYS72 | |
| B | HIS75 | |
| C | CYS5 | |
| C | CYS8 | |
| C | CYS16 | |
| C | CYS19 | |
| C | CYS26 | |
| A | CYS16 | |
| C | CYS29 | |
| C | HIS33 | |
| C | HIS39 | |
| C | CYS50 | |
| C | CYS55 | |
| C | CYS72 | |
| C | HIS75 | |
| D | CYS5 | |
| D | CYS8 | |
| D | CYS16 | |
| A | CYS19 | |
| D | CYS19 | |
| D | CYS26 | |
| D | CYS29 | |
| D | HIS33 | |
| D | HIS39 | |
| D | CYS50 | |
| D | CYS55 | |
| D | CYS72 | |
| D | HIS75 | |
| A | CYS26 | |
| A | CYS29 | |
| A | HIS33 | |
| A | HIS39 | |
| A | CYS50 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00990 |
| Chain | Residue | Details |
| A | GLY282 | |
| B | GLY282 | |
| C | GLY282 | |
| D | GLY282 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Cleavage; by 3CL-PRO => ECO:0000250|UniProtKB:P0C6V3 |
| Chain | Residue | Details |
| A | GLN601 | |
| B | GLN601 | |
| C | GLN601 | |
| D | GLN601 |
