7N8Q
Rhesusized RV305 DH677.3 Fab bound to Clade A/E 93TH057 HIV-1 gp120 core.
Summary for 7N8Q
Entry DOI | 10.2210/pdb7n8q/pdb |
Descriptor | clade A/E 93TH057 HIV-1 gp120 core, M48U1 CD4 MIMETIC PEPTIDE, Rhesusized DH677.3 FAB HEAVY CHAIN, ... (6 entities in total) |
Functional Keywords | dh677.3, hiv-1 env v2 peptide, rv144, rv305, rhesusized antibody, immune system |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 7 |
Total formula weight | 181338.50 |
Authors | Tolbert, W.D.,Pazgier, M. (deposition date: 2021-06-15, release date: 2022-04-06, Last modification date: 2023-11-15) |
Primary citation | Tolbert, W.D.,Nguyen, D.N.,Tuyishime, M.,Crowley, A.R.,Chen, Y.,Jha, S.,Goodman, D.,Bekker, V.,Mudrak, S.V.,DeVico, A.L.,Lewis, G.K.,Theis, J.F.,Pinter, A.,Moody, M.A.,Easterhoff, D.,Wiehe, K.,Pollara, J.,Saunders, K.O.,Tomaras, G.D.,Ackerman, M.,Ferrari, G.,Pazgier, M. Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s. Front Immunol, 12:787603-787603, 2021 Cited by PubMed: 35069563DOI: 10.3389/fimmu.2021.787603 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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