7N77

Cryo-EM structure of ATP13A2 D458N/D962N mutant in the AlF-bound E1P-like state

Summary for 7N77

• Entry DOI: 10.2210/pdb7n77/pdb
• EMDB information: 24212 24213 24214 24215 24216 24217 24218 24219 24220 24221 24222 24223
• Descriptor: Isoform 3 of Polyamine-transporting ATPase 13A2, TETRAFLUOROALUMINATE ION, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: p-type atpase, p5b-atpase, polyamine transporter, transport protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 129543.23

Authors

Sim, S.I.,Park, E. (deposition date: 2021-06-09, release date: 2021-11-10, Last modification date: 2024-06-05)

• Primary citation: Sim, S.I.,von Bulow, S.,Hummer, G.,Park, E.; Structural basis of polyamine transport by human ATP13A2 (PARK9).; Mol.Cell, 81:4635-4649.e8, 2021; PubMed: 34715013; DOI: 10.1016/j.molcel.2021.08.017

Experimental method

ELECTRON MICROSCOPY (3.2 Å)