7N77
Cryo-EM structure of ATP13A2 D458N/D962N mutant in the AlF-bound E1P-like state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Isoform 3 of Polyamine-transporting ATPase 13A2 | polymer | 1175 | 128442.5 | 1 | UniProt (Q9NQ11) Pfam (PF12409) Pfam (PF00122) Pfam (PF13246) | Homo sapiens (Human) | |
| 2 | B (A) | TETRAFLUOROALUMINATE ION | non-polymer | 103.0 | 1 | Chemie (ALF) | |||
| 3 | C (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 4 | D, E (A) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 2 | Chemie (Y01) | |||
| 5 | F (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 1 - 1175 (UniProt: Q9NQ11)
| PDB | External Database | Details |
|---|---|---|
| Asn 458 | Asp 458 | engineered mutation |
| Asn 962 | Asp 962 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 128442.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1100.7 | |
| All* | Total formula weight | 129543.2 |
