7N42

Crystal structure of the tandem bromodomain of human TAF1 (TAF1-T) bound to ZS1-681

Summary for 7N42

• Entry DOI: 10.2210/pdb7n42/pdb
• Descriptor: Transcription initiation factor TFIID subunit 1, 1,2-ETHANEDIOL, 6-(but-3-en-1-yl)-4-[6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one, ... (5 entities in total)
• Functional Keywords: bromodomain, taf1, non-bet, bet, kinase inhibitor, atr, dual brd-kinase, transferase, gene regulation
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 31980.45

Authors

Karim, M.R.,Schonbrunn, E. (deposition date: 2021-06-03, release date: 2021-06-09, Last modification date: 2023-10-18)

• Primary citation: Karim, M.R.,Schonbrunn, E.; Crystal structure of the tandem bromodomain of human TAF1 (TAF1-T) bound to ZS1-681; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.9 Å)