7N42
Crystal structure of the tandem bromodomain of human TAF1 (TAF1-T) bound to ZS1-681
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcription initiation factor TFIID subunit 1 | polymer | 265 | 30968.3 | 1 | UniProt (P21675) Pfam (PF00439) | Homo sapiens (Human) | Cell cycle gene 1 protein,TBP-associated factor 250 kDa,p250,Transcription initiation factor TFIID 250 kDa subunit,TAFII250 |
| 2 | B, C, D, E, F... (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 3 | I (A) | 6-(but-3-en-1-yl)-4-[6-{1-[(R)-S-methanesulfonimidoyl]cyclopropyl}-2-(1H-pyrrolo[2,3-b]pyridin-4-yl)pyrimidin-4-yl]-1,6-dihydro-7H-pyrrolo[2,3-c]pyridin-7-one | non-polymer | 499.6 | 1 | Chemie (06M) | |||
| 4 | J (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 5 | K (A) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
A: 1373 - 1635 (UniProt: P21675)
| PDB | External Database | Details |
|---|---|---|
| Ser 1371 | - | expression tag |
| Met 1372 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 30968.3 | |
| Non-Polymers* | Number of molecules | 9 |
| Total formula weight | 1012.2 | |
| All* | Total formula weight | 31980.5 |
