7N0C

Cryo-EM structure of the monomeric form of SARS-CoV-2 nsp10-nsp14 (E191A)-RNA complex

Summary for 7N0C

• Entry DOI: 10.2210/pdb7n0c/pdb
• EMDB information: 24103
• Descriptor: Non-structural protein 10, Proofreading exoribonuclease, RNA (25-MER), ... (7 entities in total)
• Functional Keywords: sars-cov-2, exoribonuclease, mismatch correction, viral protein-rna complex, viral protein/rna
• Biological source: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); More
• Total number of polymer chains: 4
• Total formula weight: 97368.31

Authors

Liu, C.,Yang, Y. (deposition date: 2021-05-25, release date: 2021-07-28, Last modification date: 2021-09-22)

• Primary citation: Liu, C.,Shi, W.,Becker, S.T.,Schatz, D.G.,Liu, B.,Yang, Y.; Structural basis of mismatch recognition by a SARS-CoV-2 proofreading enzyme.; Science, 373:1142-1146, 2021; PubMed: 34315827; DOI: 10.1126/science.abi9310

Experimental method

ELECTRON MICROSCOPY (3.4 Å)