7MX2

Cryo-EM structure of human ternary NatC complex with a Bisubstrate inhibitor

Summary for 7MX2

Entry DOI	10.2210/pdb7mx2/pdb
EMDB information	24070
Descriptor	N-alpha-acetyltransferase 35, NatC auxiliary subunit, N-alpha-acetyltransferase 38, NatC auxiliary subunit, N-alpha-acetyltransferase 30, ... (5 entities in total)
Functional Keywords	natc, naa30, naa35, naa38, transferase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	116609.71
Authors	Deng, S.,Marmorstein, R. (deposition date: 2021-05-18, release date: 2022-12-14, Last modification date: 2023-06-28)
Primary citation	Deng, S.,Gardner, S.M.,Gottlieb, L.,Pan, B.,Petersson, E.J.,Marmorstein, R. Molecular role of NAA38 in thermostability and catalytic activity of the human NatC N-terminal acetyltransferase. Structure, 31:166-173.e4, 2023 Cited by PubMed: 36638802 DOI: 10.1016/j.str.2022.12.008 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.64 Å)

Structure validation